Comparison of Gonadotropin-Releasing Hormone Agonists and Orchiectomy

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Comparison of Gonadotropin-Releasing Hormone Agonists and Orchiectomy: Effects of Androgen-Deprivation Therapy.

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Pulsatile administration of gonadotropin-releasing hormone agonist to gilts actively immunized against gonadotropin-releasing hormone.

Sexually mature gilts (n = 20) were actively immunized against GnRH. Primary and booster immunizations of GnRH conjugated to bovine serum albumin induced production of antibodies in all gilts. Nineteen of the gilts became acyclic with suppressed concentrations of gonadotropins and estradiol. Intravenous challenges with 100 micrograms GnRH and 5 micrograms D-(Ala6, des-Gly-NH2(10)) ethylamide Gn...

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Increasing use of gonadotropin-releasing hormone agonists for the treatment of localized prostate carcinoma.

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ژورنال

عنوان ژورنال: JAMA Oncology

سال: 2016

ISSN: 2374-2437

DOI: 10.1001/jamaoncol.2015.4917